Search Result

Search Results for " interferon, γ "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T4403	AX-024 hydrochloride	AX-024 HCl	IL Receptor , TNF , COX , IFNAR , Interleukin
	AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.		IL Receptor , TNF , COX , IFNAR , Interleukin
T76742	Emapalumab	NI-0501	COX
	Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab ha...		COX
T26895	BRD0476	BRD-0476,ML 187,ML187,ML-187,BRD 0476
	BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell ...
T76637	IFN-γ Antagonist 1
	IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells, demonstrating an IC50 of approximately 35 μM. This compoun...
T76638	IFN-γ Antagonist 1 acetate
	IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate, an interferon γ (IFN γ) antagonist, effectively inhibits the expression of HLR/DR antigen in Colon 205 cells induced by IFN-γ, with an inhibition concentration (IC 50)...
T81331	QL-1200186		JAK
	QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following interleukin-12 (IL-12) stimulation and markedly improves skin le...		JAK
T70291	PCC0208018
	PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programm...
T77003	Ezabenlimab
	Ezabenlimab (BI-754091) is an anti-PD-1 monoclonal antibody (mAb) that exhibits a binding constant (Kd) of 6 nM in CHO cells. It effectively inhibits the interaction between PD-1 and its ligands, PD-L1 and PD-L2, enhanci...
T61574	PD-L1-IN-1
	PD-L1-IN-1, a powerful PD-L1 inhibitor, demonstrated an IC50 of 115 nM. By forming a robust bond with the PD-L1 protein, PD-L1-IN-1 effectively suppressed tumor growth by enhancing the antitumor immune activity of periph...
T81697	NBI-6024
	NBI-6024, an altered peptide ligand (APL), serves as an epitope for interferon-gamma-producing T helper lymphocytes associated with inflammation in patients with type 1 diabetes [1] [2].
T83846	HOXB7 (8-25) TFA	Homeobox B7 (8-25)
	HOXB7 (8-25), a peptide fragment derived from homeobox B7 (HOXB7)—a key controller of cell growth and oncogene activator—facilitates antigen presentation when pulsed onto dendritic cells obtained from human peripheral bl...
T61968	PD-1/PD-L1-IN 6
	PD-1/PD-L1-IN 6 (compound A13) is a potent inhibitor of PD-1/PD-L1 interaction (IC 50 = 132.8 nM). PD-1/PD-L1-IN 6 shows outstanding immunoregulatory activity. In a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, PD-1...
T82071	Influenza NP (311-325)
	Influenza NP (311-325) is a biologically active peptide composed of amino acids 311 to 325 derived from the influenza virus nucleoprotein (NP). As a bona fide MHC class II-restricted epitope, it is instrumental for study...

Compounds

AX-024 hydrochloride

T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

Synonym: BRD-0476,ML 187,ML187,ML-187,BRD 0476

IFN-γ Antagonist 1 acetate

Synonym: Homeobox B7 (8-25)

Influenza NP (311-325)

T82071

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
TQ0273	Neopterin	D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one	Endogenous Metabolite
	D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ. In humans, neopterin is involved in purine biosynthesis.		Endogenous Metabolite
T14854	Caerulomycin A	Cerulomycin,Caerulomycin	Antifungal
	Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antif...		Antifungal
T5681	ETHYL CAFFEATE	ETHYL 3,4-DIHYDROXYCINNAMATE	NF-κB , COX , PGE Synthase , NO Synthase
	Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s...		NF-κB , COX , PGE Synthase , NO Synthase

Natural Products

Neopterin

TQ0273

Synonym: D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one

Target: Endogenous Metabolite

Caerulomycin A

T14854

Synonym: Cerulomycin,Caerulomycin

Target: Antifungal

ETHYL CAFFEATE

T5681

Synonym: ETHYL 3,4-DIHYDROXYCINNAMATE

Target: NF-κB, COX, PGE Synthase, NO Synthase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00047	IFN gamma Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi...
TMPY-02827	IFN gamma Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	IFN gamma Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01581.
TMPY-01714	IFN gamma Protein, Human, Recombinant	Human	CHO Cells
	IFN gamma Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 16.7 kDa and the accession number is A0A7R8GUN6.
TMPY-03356	IFN gamma Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	IFN gamma Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.5 kDa and the accession number is A0A7R8C347.
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-01151	IFNGR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IFNGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.3 kDa and the accession number is A0A0S2Z3Y2.
TMPY-02355	IFNGR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IFNGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P15261.
TMPK-00048	IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi...
TMPY-03664	IFN gamma Protein, Ferret, Recombinant (His)	Ferret	HEK293 Cells
	IFN gamma Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A4PIZ9.
TMPY-04191	IFN gamma Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	IFN gamma Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.2 kDa and the accession number is G7N7K9.
TMPY-00527	IFN gamma Protein, Rhesus, Recombinant	Rhesus	E. coli
	IFN gamma Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.9 kDa and the accession number is G7N7K9.
TMPY-02323	IFN gamma Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IFN gamma Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17 kDa and the accession number is P01580.
TMPY-02322	IFN gamma Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IFN gamma Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01580.
TMPY-03346	IFNGR1 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	IFNGR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q6P6T3.
TMPY-03379	IFNGR1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	IFNGR1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.8 kDa and the accession number is G7P327.
TMPY-02122	IFNGR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disea...
TMPY-03668	IFNGR1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IFNGR1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is G7P327.
TMPY-05831	IFNGR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IFNGR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.51 kDa and the accession number is A0A0S2Z3Y2.
TMPJ-01056	IL-18 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63...
TMPJ-00884	CXCL9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor foun...
TMPJ-01084	CXCL9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b...
TMPY-02354	IFNGR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IFNGR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53 kDa and the accession number is P15261.
TMPY-02887	IFI30 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putat...
TMPJ-00070	IL-18 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c...
TMPJ-00008	CXCL10 Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX...
TMPJ-00072	IL-18BPd Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interact...
TMPK-00237	2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated	Human	HEK293 Cells
	2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports ha...